MPSC Drug Inspector GSS Gr-B Question Paper 2008

Updated on May 5, 2018
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MPSC Drug Inspector GSS Gr-B Question Paper 2008

  1. Which enzyme is used by the HIV to from DNA in the host cell?

(1) Endonuclease

(2) Reverse transcriptase

(3) Isomerase

(4) None of the above

  1. Mumps is an acute disease caused by_______ organism

(1) HIV

(2) Paramyxovirus

(3) Poliovirus

(4) Hepatitis virus

  1. The agents that control the growth of micro-organisms on inanimate objects are referred as______.

(1) Sterilants

(2) Antiseptics

(3) Antibiotics

(4) disinfectants

  1. Preservatives are not to be formulations of injectables, administered by ______ route.

(1) Intramuscular

(2) Subcutaneous

(3) Intraocular

(4) Intradermal

  1. In the LAL test ______ cells are used for the detection of pyrogen.

(1) Plasma

(2) Lymphocyte

(3) Red blood

(4) Amoebocyte

  1. Which one of the following is not a Sexually Transmitted Disease (STD)

(1) Gonorrhea

(2) Syphilis

(3) Chancroid

(4) Hepatitis

  1. In an autoclave, the sterilization by moist heat is carried out at_______.

(1) 1600C for 1 hour

(2) 1800C for 30 minutes

(3) 1210C and 15 psi pressure for 15 minutes

(4) 1000C and 10 psi pressure for 10 minutes

  1. The limit test for acid-insoluble ash gives_____ impurities.

(1) Inorganic impurities

(2) Organic impurities

(3) Siliceous impurities

(4) None of the above

  1. Which of the following equations is useful in calculating shelf life of Pharmaceuticals in accelerated stability testing?

(1) Noye’s Whitney Equation

(2) Gibb’s Helmholtz Equation

(3) Arrhenius Equation

(4) Stokes Equation

  1. A drug sample, taken by the drug inspector for analysis is sent to_______.

(1) Drug Controller

(2) Chief Inspector

(3) Government Analyst

(4) Public Testing Laboratory

  1. Central Register of Pharmacists is maintained by______

(1) State Health Ministry

(2) Pharmacy Council of India

(3) State Pharmacy Council

(4) Drug Controller of India

  1. The drug______ is not included in the First Schedule of DPCO.

(1) Rifampicin

(2) Paracetamol

(3) Aspirin

(4) Vitamin C

  1. A local anaesthetic agent suitable only for injection is_______.

(1) Tetracaine

(2) Benzocaine

(3) Dibucaine

(4) Procaine

  1. In a person infected with HBV, the first virological marker detectable in serum is______

(1) HBsA

(2) HBcA

(3) HBeA

(4) Anti HBs

  1. Which of the following drug is preferred for prevention and treatment of osteoporosis postmenopausal womwn?

(1) Raloxifene

(2) Tamoxifen

(3) Ormeloxifene

(4) Toremifene

16.The common carrier, used in vaccine formulation is:

(1) Alum

(2) Silica

(3) Calcium carbonate

(4) Mineral oil

  1. Which of these cannot be an OTC drug?

(1) Antacids

(2) Antibiotics

(3) Multivitamin syrup

(4) Calcium tablets

  1. Which of the following blocks Folic acid Synthesis?

(1) Sulfanilamide

(2) Carbonylamide

(3) Alkylamide

(4) Acrylamide

  1. Any person, aggrieved by any notification, issued regarding Drugs (Price Control) order, may apply to Government for a review within _______ of publication in the official gazette.

(1) 10 days

(2) 30 days

(3) 15 days

(4) 6 months

  1. One term in the number series is wrong. Find out the wrong term.

2,5,10,50,500,5000

(1) 5

(2) 10

(3) 50

(4) 5000

  1. The purpose of combined drug regimen in tuberculosis is mainly:

(1) To increase the duration of active therapy

(2) To delay the emergence of drug resistance

(3) Promote placebo effe3ct on the patient

(4) To get better effect

  1. All amino used in protein biosynthesis have atleast one asymmetric center except

(1) Methionine

(2) Arginine

(3) Glycine

(4) Tyrosine

  1. Which of the following personal is not required for the operation of a blood bank facility?

(1) Medical officer

(2) Registered nurse

(3) Blood bank technician possessing DMLT

(4) Medical social worker

  1. With regard to the use of nitrates, one of the following statements is correct:

(1) Tolerance occurs only to the adverse effects and not to the antinational effect

(2) Nitrates have diuretic effect

(3) Gleceryl trinitrate is given to relieve angina rapidly

(4) Are the drugs of choice in hypertension

  1. Vaccine – preventable diseases include all except

(1) Measles

(2) Typhoid

(3) Japanese Encephalis

(4) AIDS

  1. Which of the following is the sole bearer of genetic information (normally)?

(1) m-RNA

(2) DNA

(3) r-RNA

(4) Chromatin

  1. Which of the following is not a macrocline antibiotic?

(1) Erythromycin

(2) Roxithromycin

(3) Terramycin

(4) Clarithromycin

  1. Production of which of the following is a characteristic feature of staphylococcal food poisoning?

(1) Neurotoxin

(2) Enterotoxin

(3) Cytotoxin

(4) Endotoxin

  1. “Hirudin”

(1) Coagulates blood

(2) Acts as a heparin substitute and inhibits thrombin

(3) Is found in human saliva

(4) Is an antidote of heparin

  1. As per Gmp guidelines the permitted limit of solid content in water for injection is:

(1) 100 ppm

(2) 1 ppm

(3) 10 ppm

(4) 0.10 ppm

  1. HLB values of four surfactants are listed below. Which of them is suitable for use as a W/o emulsifier?

(1) A – 20

(2) B – 2.1

(3) C – 13.3

(4) D – 4.7

  1. All of the following are features of Nimesulide except_______

(1) Less oral absorption

(2) Weak cox inhibitor

(3) High protein binding

(4) Potent anti inflammatory action

  1. The plasmids conferring drug resistance are called______.

(1) R-plasmids

(2) col-plasmids

(3) Cryptic- plasmids

(4) degradative plasmids

  1. the double helix model of DNA was proposed by______.

(1) Watson and Crick

(2) Charagoff

(3) Robinson

(4) Krebs

  1. All the drugs are narcotic except:

(1) Opium

(2) Cannabis

(3) Hemp

(4) Cinchona

  1. The active proteolytic enzyme in gastric juice is:

(1) Pepsinogen

(2) Pepsin

(3) Trypsin

(4) Gastrin

  1. Which of the following compounds is added as a reducing compound to a medium to decrease its oxygen content?

(1) Sodium Taurocholate

(2) Sodium Hydrogen Phosphate

(3) Sodium Cyanide

(4) Sodium Thioglycolate

  1. Squeezing of WBCs through the pores of blood capillaries is called as_______

(1) Passive diffusion

(2) Diapedesis

(3) Chemotaxis

(4) Pinocytosis

  1. The most dangerous situation amongst the following is_________.

(1) Rh negative mother bearing her first Rh positive child

(2) Rh negative mother bearing her second Rh positive child

(3) Rh negative mother bearing her first Rh negative child

(4) Rh negative mother bearing her Second Rh negative child

  1. Erythroblastosis fetalis is a :

(1) Hemolytic disease of the new-born related to blood groups

(2) Type of anemia

(3) Disease related to bone marrow

(4) Decrease in while blood cell count

  1. Which process leads to a change from liquid to solid form, causing denaturation of proteins?

(1) Precipitation

(2) Coagulation

(3) Agglutination

(4) Centrifugation

  1. Penicillin G continues to be the first line treatment for following disease, as the causative organism has not developd resistance as yet_______.

(1) Gonorrhoea

(2) Syphilis

(3) Staphylococcal abscess

(4) H. influenza meningitis

  1. Which of the following untoward effect is shared by both phenobarbitone and phenytoin?

(1) Sedation

(2) Megaloblastic anaemia

(3) Hirsuitism

(4) Gingival hyperplasia

  1. ______ viruses are detected by haemagglutination test.

(1) Rabbies

(2) Polio

(3) Influenza

(4) Rubella

  1. ______ is a causative agent of tuberculosis.

(1) Streptococcus

(2) Staphylococcus

(3) Mycobacterium

(4) Pseudomonas

  1. ISO 14000 is concerned with_______.

(1) Quality management systems

(2) Guidelines for performance of quality management

(3) Environmental safety

(4) Information – processing system

  1. As an anticoagulant, aspirin differs from coumarin in which of the following respects?

(1) Being synthetic in nature

(2) Mechanism of action

(3) Route of administration

(4) Therapeutic use

  1. Whole human blood is stored at______

(1) – 200C

(2) 8 – 100C

(3) 2 – 80C

(4) 00C

  1. A man said to a lady, “your mother’s husband’s sister is my aunt.” How is the lady related to the man?

(1) Daughter

(2) Grand daughter

(3) Mother

(4) Sister

  1. Which of the following antidiabetic drug (oral) does not stimulate insulin secretion?

(1) Nateglinide

(2) Repaglinide

(3) Glyburide

(4) Metformin

  1. The polyene antibiotics primarily act by______

(1) Inhibiting fungal ergosterol synthesis

(2) Creating micropores in fungal cell membrane

(3) Inhibiting fungal DNA synthesis

(4) Disorienting microtubules in fungal cells

  1. Ployamide sutures are_______

(1) natural absorbable

(2) Synthetic absorbable

(3) Natural nonabsorbable

(4) Synthetic nonabsorbable

  1. Morphine can be used for all the following therapeutic purposes except:

(1) To relieve the pain of myocardial infarction

(2) To Provide sedation and analgesia infarction

(3) To relieve cancer pain

(4) To relieve pain caused by severe head injury

  1. The analysis of biological fluids for sodium, potassium, calcium ions can done, using:

(1) Flourimetry

(2) Colourimetry

(3) Flame photometry

(4) Potentiometry

  1. Which of the following can modify the effect of a drug?

(1) Formulation of the drug

(2) Age, sex, genetic, factors

(3) Immune status of the patient

(4) Excipients in the formulation

  1. which one of these sweeteners is carcinogenic?

(1) Saccharin

(2) Sucrose

(3) Mannitol

(4) Glycerine

  1. Specific agglutinins of ABO system have the following features, except______.

(1) are gamma globulins

(2) are produced by bone marrow and lymph glands

(3) are present right at birth

(4) are produced in people who do not have the respective agglutinogen in their RBCs

  1. Colloid osmotic pressure of blood is mostly contributed by_______

(1) Blood cells

(2) Albumin

(3) Plasma electrolytes

(4) Fibrinogen

  1. Storage temperature for water for injection is________

(1) R.T (Room temperature)

(2) 500C

(3) 800C

(4) 370C

  1. Which of the following herbs is considered as valuable ‘Nutraceutical’?

(1) Senna

(2) Spirulina

(3) Vasaka

(4) Bael

  1. Amit goes 30 metres North, then turns right and walks 40 meters, then again turns right and walks 20 meters, then again turns right and walks 40 meters. How many metres is he from his orginnal position?

(1) 0

(2) 10

(3) 20

(4) 40

  1. Pointing to a lady in the photograph, Dev Anand said, “This woman is my sister’s father’s son-in-law’s wife”. How is Dev Anand related to the woman?

(1) Mother

(2) Sister

(3) Wife

(4) Cannot be determine

63.Which of the following metal binding agents inhibits the growth of anaerobic bacteria, except Lactic acid bacteria?

(1) Sodium citrate

(2) Sodium azide

(3) Sodium nitrate

(4) Sodium acetate

  1. Neutralization test is generally metal binding agents inhibits the growth of anaerobic bacteria, except Latic acid bacteria?

(1) Sodium citrate

(2) Sodium azide

(3) Sodium nitrate

(4) Sodium acetate

  1. Neutralization test is generally used for the serodiagnosis of_______ infections.

(1) Viral

(2) Bacterial

(3) Fungal

(4) Protozoan

  1. Which one of the following statements about eosinophils is incorrect?

(1) Present numerously in blood

(2) Are weak phagocytes

(3) Shows chemotaxis

(4) Releases modified lysosomes

  1. Widal test is used for diagnosis of______ disease.

(1) Dysentery

(2) Tuberculosis

(3) Typhoid

(4) Leprosy

  1. Essential Drugs are those which should be available in every:

(1) Chemist shop

(2) Primary health centre

(3) Private hospital

(4) Nursing home

  1. The magic remedies Act was passed and enforced in the year________

(1) 1954

(2) 1919

(3) 1930

(4) 1940

  1. What is chelating capacity of one hundred milligram of desferrioxamine in terms of milligrams of iron?

(1) 4.5

(2) 8.5

(3) 6.5

(4) 10.5

  1. A goes 4 km South, then 8 km West , then 6 km North, then 8 km East and then 2 km South. How far is A from the starting point?

(1) 2 km

(2) 1 km

(3) 0 km

(4) 3 km

  1. The cultivation of opium poppy and production of opium are to be superbised by:

(1) Narcotics Inspector

(2) Drug Controller

(3) Narcotics Commissioner

(4) Narcotics Consultative Committee

  1. UV spectroscopy is not useful for identification of______

(1) Compounds with double bonds

(2) Compounds with conjugated double bonds

(3) Poly-aromatic compounds

(4) Alkanes

  1. If a drug is not labeled in prescribed manner, it is known as_______.

(1) Spurious drug

(2) Misbranded drug

(3) Genuine drug

(4) Adulterated drug

  1. Which of the following vaccines is included under Universal Immunization Programme but not under India Immunisation Schedule?

(1) Measles

(2) Hepatitis B

(3) Hi B

(4) Tetanus

  1. The molecular weight of any organic compound can be determined by_______ spectrometry.

(1) IR

(2) UV

(3) NMR

(4) MS

  1. Laminar air flow is used for______.

(1) aseptic technic

(2) inclubation

(3) Fermentation

(4) Detection of specific gravity

  1. Aseptic filling of injections is to be carried out in facility complying to grade ______

(1) A

(2) B

(3) C

(4) D

  1. Which of the following vaccines is used as an adjuvant in immunotherapy of cancer?

(1) BCG
(2) DPT

(3) TAB
(4) Mumps

  1. The medicinal ‘hemp’ includes:

(1) Tincture of ‘hemp’

(2) Aerial parts of ‘hemp’ tree

(3) Extract of ‘hemp’

(4) All the above